Developing next generation treatments to preserve vision for patients with diseases affecting the back of the eye

Angiopoietin-2 stimulation of endothelial cells induces alphavbeta3 integrin internalization and degradation.

Thomas,M., Felcht,M., Kruse,K., Kretschmer,S., Deppermann,C., Biesdorf,A., Rohr,K., Benest,A.V., Fiedler,U., and Augustin,H.G. 2010. Angiopoietin-2 stimulation of endothelial cells induces alphavbeta3 integrin internalization and degradation. J. Biol. Chem. 285, 23842-23849.