Developing next generation treatments to preserve vision for patients with diseases affecting the back of the eye

Deletion of placental growth factor prevents diabetic retinopathy and is associated with Akt activation and HIF1alpha-VEGF pathway inhibition.

Huang,H., He,J., Johnson,D., Wei,Y., Liu,Y., Wang,S., Lutty,G.A., Duh,E.J., and Semba,R.D. 2015. Deletion of placental growth factor prevents diabetic retinopathy and is associated with Akt activation and HIF1alpha-VEGF pathway inhibition. Diabetes 64, 200-212.