Delivering next-generation treatments for back of the eye disorders, with focus on diabetic eye disease

Extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation.

Gao,B.B., Clermont,A., Rook,S., Fonda,S.J., Srinivasan,V.J., Wojtkowski,M., Fujimoto,J.G., Avery,R.L., Arrigg,P.G., Bursell,S.E., Aiello,L.P., and Feener,E.P. 2007. Extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation. Nat. Med. 13, 181-188.