Developing next generation treatments to preserve vision for patients with diseases affecting the back of the eye

Stable and long-lasting, novel bicyclic peptide plasma kallikrein inhibitors for the treatment of diabetic macular edema

Daniel P. Teufel, Gavin Bennett, Helen Harrison, Katerine van Rietschoten, Silvia Pavan, Catherine Stace, François Le Floch, Tine Van Bergen, Elke Vermassen, Philippe Barbeaux, Tjing-Tjing Hu, Jean HM Feyen, Marc Vanhove. 2018. Stable and long-lasting, novel bicyclic peptide plasma kallikrein inhibitors for the treatment of diabetic macular edema. J Med Chem. 

https://www.ncbi.nlm.nih.gov/pubmed/29517911
Publication date: 
April, 2018